Sam Warburton will hope to lead Wales to another Six Nations title (Getty Images)
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In Saturday's early kick off Wales will take on Italy at the Stadio Olimpico knowing that they need to win by a sizeable margin to stand a realistic chance of taking the Six Nations title.
Wales sit third in the table, joint on points with England and Ireland, but with an inferior points difference of 25 less than leaders England, they will be looking to pile on the points and post a target for their title rivals to chase later in the day.
Warren Gatland has made two injury-enforced changes to his starting line up ahead of Wales' trip to Rome.
Rob Evans makes his first start at loosehead prop and Aaron Jarvis comes in at tighthead, in the absence of Gethin Jenkins and Samson Lee.
Six Nations 2015 in pictures
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Scarlets half-back Gareth Davies could come on to make his second appearance for Wales as he starts as a replacement, ahead of Mike Philips, who drops out of the match-day squad.
Ken Owens has been called up to the bench as injury cover for Richard Hibbard. Scott Andrew, Rhys Gill have also been named as replacements.
Lee ruptured an Achilles tendon in the first scrum of the game against Ireland last Saturday and Gethin Jenkins is out after failing to recover from the hamstring injury that forced him off at half time.
The Welsh have not lost to the Azzurri since 2007 but they only beat Italy by eight points when the teams last met and have not won by a bigger margin than seven in this years tournament.
Leonardo Ghiraldini will captain Italy in the absence of Sergio Parisse (Getty Images)
As always, Italy are in no position to challenge for the title at this stage of the tournament, however, they will be desperate to improve on last weekend's poor performance.
Jacques Brunel has made four changes to the team that started against France and will be without his talismanic captain for his sides last game of the tournament.
Sergio Parisse limped from the field against France after sustaining a foot injury so his fellow centurion Mauro Bergamasco comes into the back row and Samuela Vunisa fills in at number eight.
Italy will also start with a new pair of props, Martin Castrogiovanni replaces Dario Chistolini and Michele Rizzo takes over from Matias Aguero.
Fit-again Kelly Haimona starts at fly half, in the absence of the injured Tommy Allan.
The Azzurri failed to score at home for the first time in their Six Nations history last Sunday but they have already spared themselves from a second successive wooden spoon with a sole win over Scotland in this years competition.
TEAMS:
Wales: Leigh Halfpenny (Toulon), George North (Northampton Saints), Jonathan Davies (ASM Clermont Auvergne), Jamie Roberts (Racing Metro), Liam Williams (Scarlets); Dan Biggar (Ospreys), Rhys Webb (Ospreys); Rob Evans (Scarlets), Scott Baldwin (Ospreys), Aaron Jarvis (Ospreys), Luke Charteris (Racing Metro), Alun Wyn Jones (Ospreys), Dan Lydiate (Ospreys), Sam Warburton (Cardiff Blues, capt), Taulupe Faletau (Newport Gwent Dragons).
Replacements: Ken Owens (Scarlets), Rhys Gill (Saracens), Scott Andrews (Cardiff Blues), Jake Ball (Scarlets), Justin Tipuric (Ospreys), Gareth Davies (Scarlets), Rhys Priestland (Scarlets), Scott Williams (Scarlets).
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