Premier League team news: How Liverpool, Man Utd, Arsenal, Chelsea, Tottenham and City will line-up

Here is how we are predicting the Premier League’s ‘big six’ to line-up this weekend

Premier League football makes its eagerly anticipated return this weekend after a two-week hiatus during the international break.

There are games throughout the weekend and on Monday night, with Liverpool kicking off the weekend at home to Newcastle in the lunchtime game on Saturday.

Elsewhere there are crucial 3pm fixtures as teams look to challenge the top six dynasty, with Leicester travelling to Man United and Wolves hosting Chelsea at Molineux.

Roy Hodgson, after winning at Old Trafford two weeks ago, will be hoping he can work another minor miracle as Crystal Palace take on Spurs at the Tottenham Hotspur Stadium.

Arsenal take on Watford on Sunday afternoon, and will be hoping the Hornets do not benefit from a new manager bounce after they replaced Javi Gracia with Quique Sanchez Flores after just one point from four games. Here is how we think the big six will line up this weekend.

Liverpool (vs Newcastle)

Adrian will continue in place of Alisson

With Alisson still recovering from an injury he suffered in the opening game of the season, Adrian will continue in goal. Joel Matip has been preferred to Joe Gomez in recent weeks to partner Virgil van Dijk at the back, and the Cameroonian is likely to retain his place.

The biggest headache Jurgen Klopp has is whether to start Alex Oxlade-Chamberlain in midfield ahead of Jordan Henderson or Gini Wijnaldum. It would be harsh to drop Wijnaldum, who scored in both of the Netherlands' wins over the international break.

Manchester United (vs Leicester)

Pogba is out for United

After United’s unbelievable 4-0 opening day win over Chelsea, their season has been on a slight downward turn which could continue this weekend as their squad has been hit by injuries.

Paul Pogba, Anthony Martial and Luke Shaw are all definitely out of the game, whilst Solskjaer has stated that Aaron Wan-Bissaka and Jesse Lingard are only “maybes”. This injury crisis could open the door for Nemanja Matic to make his first start of the season, having only played 22 minutes thus far in United’s last match against Southampton.

Chelsea (vs Wolves)

Kante is out for the Blues

Chelsea have also made an indifferent start to the season, and they too are suffering with injuries. The Blues have been boosted by Callum Huson-Odoi and Reece James returning to training, but this game will come too soon for them. The same is true of Antonio Rudiger, though the German may make the matchday squad.

Mateo Kovacic and Emerson have picked up injuries in the last few weeks, and join Pedro and N’Golo Kante in struggling for fitness ahead of the trip to Wolves.

Spurs (vs Palace)

Walker-Peters could start for Spurs

Mauricio Pochettino confirmed that Tanguy Ndombele, Ryan Sessengon and Kyle Walker-Peters will have their injuries assessed ahead of Saturday’s game. If Ndombele is deemed unfit, it is likely Pochettino will switch from a diamond to a 4-2-3-1, with Lucas or Lamela featuring from the right.

Giovani Lo Celso will not feature for a few weeks, after picking up an injury over the break on duty with Argentina but Dele Alli has continued his comeback over the last fortnight after not being included in the England squad.

Manchester City (vs Norwich)

Sterling will hope to continue his fine form

Pep Guardiola has a big decision to make at right-back, with new signing Joao Cancelo not yet trusted with a Premier League start ahead of Kyle Walker. There are fewer options in the middle of the defence, with John Stones and Nicolas Otamendi the only recognised centre-backs.

Ilkay Gundogan picked up a knock with Germany so David Silva should continue in midfield, and it is still unclear whether Guardiola prefers Fernandinho or new signing Rodri in the holding role.

Arsenal (vs Watford)

Xhaka will retain his place in the XI

The Gunners are yet another club with injuries aplenty, with Joe Willock, Granit Xhaka and Lucas Torreira all facing a race to be fit for the trip to Vicarage Road. Kieran Tierney and Hector Bellerin have been spotted in training, but it will be a few weeks before we see them in first-team action.

Nicolas Pepe sat out of the Ivory Coast squad to work closely with the Arsenal coaches as he continues to acclimatise to the Premier League. Pepe is expected to once again link up with Pierre-Emerick Aubameyang and Alex Lacazette in Arsenal’s new-look front line.